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Size-dependent resistance of human tumour spheroids to photodynamic treatment.
Spheroids derived from the human colon adenocarcinoma cell line, WiDr, were exposed to 10 micrograms ml-1 Photofrin II and irradiated with light (700 nm, 50 mW cm-2). Compared with exponentially growing monolayer cultures, cells in spheroids of 100, 250 and 500 microns diameter were respectively 1.8...
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
1989
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247149/ https://www.ncbi.nlm.nih.gov/pubmed/2523722 |