Thyroid epithelial cell transformation by a retroviral vector expressing SV40 large T.

A recombinant murine retroviral vector encoding the SV40 virus large T antigen was used to infect stably an immortal line of differentiated rat thyroid epithelial cells, FRTL-5. Expression of SV40 T transformed these cells to anchorage independence and tumorigenicity but did not alter morphology or...

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Detalles Bibliográficos
Autores principales: Burns, J. S., Lemoine, L., Lemoine, N. R., Williams, E. D., Wynford-Thomas, D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247228/
https://www.ncbi.nlm.nih.gov/pubmed/2544221

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