Cargando…
Effects of localised tumour hyperthermia on pimonidazole (Ro 03-8799) pharmacokinetics in mice.
We have investigated the effects of localised tumour hyperthermia (LTH; 43.5 degrees C x 30 min) on the acute toxicity and pharmacokinetics of the hypoxic cell sensitizer pimonidazole (Ro 03-8799) in mice. There were three treatment groups: unrestrained controls, sham-treated and LTH treated mice. L...
Autores principales: | Walton, M. I., Bleehen, N. M., Workman, P. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1989
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247237/ https://www.ncbi.nlm.nih.gov/pubmed/2736198 |
Ejemplares similares
-
The effects of whole body hyperthermia on the pharmacokinetics and toxicity of the basic 2-nitroimidazole radiosensitizer Ro 03-8799 in mice.
por: Walton, M. I., et al.
Publicado: (1987) -
Effects on intermediary metabolism in mouse tissues by Ro-03-8799.
por: Tamulevicius, P., et al.
Publicado: (1987) -
The radiosensitizer Ro 03-8799 and the concentrations which may be achieved in human tumours: a preliminary study.
por: Saunders, M. I., et al.
Publicado: (1982) -
Effect of the nitroimidazole Ro 03-8799 on the activity of chemotherapeutic agents against a murine tumour in vivo.
por: Sheldon, P. W., et al.
Publicado: (1984) -
The effect of systemic hyperthermia on melphalan pharmacokinetics in mice.
por: Honess, D. J., et al.
Publicado: (1985)