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Phase II study of intraperitoneal recombinant interleukin-12 (rhIL-12) in patients with peritoneal carcinomatosis (residual disease < 1 cm) associated with ovarian cancer or primary peritoneal carcinoma
BACKGROUND: Pharmacokinetic advantages of intraperitoneal (IP) rhIL-12, tumor response to IP delivery of other cytokines as well as its potential anti-angiogenic effect provided the rationale for further evaluation of IPrhIL-12 in patients with persistent ovarian or peritoneal carcinoma. METHODS: A...
Autores principales: | Lenzi, Renato, Edwards, Robert, June, Carl, Seiden, Michael V, Garcia, Michael E, Rosenblum, Michael, Freedman, Ralph S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248163/ https://www.ncbi.nlm.nih.gov/pubmed/18076766 http://dx.doi.org/10.1186/1479-5876-5-66 |
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