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Self-excision of the BAC sequences from the recombinant Marek's disease virus genome increases replication and pathogenicity

Cloning of full length genomes of herpesviruses as bacterial artificial chromosomes (BAC) has greatly facilitated the manipulation of the genomes of several herpesviruses to identify the pathogenic determinants. We have previously reported the construction of the BAC clone (pRB-1B5) of the highly on...

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Detalles Bibliográficos
Autores principales:	Zhao, Yuguang, Petherbridge, Lawrence, Smith, Lorraine P, Baigent, Sue, Nair, Venugopal
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248170/ https://www.ncbi.nlm.nih.gov/pubmed/18230192 http://dx.doi.org/10.1186/1743-422X-5-19

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