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Three factors underlying incorrect in silico predictions of essential metabolic genes
BACKGROUND: The indispensability of certain genes in an organism is important for studies of microorganism physiology, antibiotic targeting, and the engineering of minimal genomes. Time and resource intensive genome-wide experimental screens can be conducted to determine which genes are likely essen...
Autores principales: | Becker, Scott A, Palsson, Bernhard O |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248557/ https://www.ncbi.nlm.nih.gov/pubmed/18248675 http://dx.doi.org/10.1186/1752-0509-2-14 |
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