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Identifying Selected Regions from Heterozygosity and Divergence Using a Light-Coverage Genomic Dataset from Two Human Populations

When a selective sweep occurs in the chromosomal region around a target gene in two populations that have recently separated, it produces three dramatic genomic consequences: 1) decreased multi-locus heterozygosity in the region; 2) elevated or diminished genetic divergence (F(ST)) of multiple polym...

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Detalles Bibliográficos
Autores principales: Oleksyk, Taras K., Zhao, Kai, De La Vega, Francisco M., Gilbert, Dennis A., O'Brien, Stephen J., Smith, Michael W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248624/
https://www.ncbi.nlm.nih.gov/pubmed/18320033
http://dx.doi.org/10.1371/journal.pone.0001712