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Role for SUR2A ED Domain in Allosteric Coupling within the K(ATP) Channel Complex

Allosteric regulation of heteromultimeric ATP-sensitive potassium (K(ATP)) channels is unique among protein systems as it implies transmission of ligand-induced structural adaptation at the regulatory SUR subunit, a member of ATP-binding cassette ABCC family, to the distinct pore-forming K(+) (Kir6....

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Detalles Bibliográficos
Autores principales: Karger, Amy B., Park, Sungjo, Reyes, Santiago, Bienengraeber, Martin, Dyer, Roy B., Terzic, Andre, Alekseev, Alexey E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248718/
https://www.ncbi.nlm.nih.gov/pubmed/18299394
http://dx.doi.org/10.1085/jgp.200709852

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