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Role for SUR2A ED Domain in Allosteric Coupling within the K(ATP) Channel Complex
Allosteric regulation of heteromultimeric ATP-sensitive potassium (K(ATP)) channels is unique among protein systems as it implies transmission of ligand-induced structural adaptation at the regulatory SUR subunit, a member of ATP-binding cassette ABCC family, to the distinct pore-forming K(+) (Kir6....
Autores principales: | Karger, Amy B., Park, Sungjo, Reyes, Santiago, Bienengraeber, Martin, Dyer, Roy B., Terzic, Andre, Alekseev, Alexey E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248718/ https://www.ncbi.nlm.nih.gov/pubmed/18299394 http://dx.doi.org/10.1085/jgp.200709852 |
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