Cargando…

DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics

Abasic sites are common DNA lesions resulting from spontaneous depurination and excision of damaged nucleobases by DNA repair enzymes. However, the influence of the local sequence context on the structure of the abasic site and ultimately, its recognition and repair, remains elusive. In the present...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jingyang, Dupradeau, François-Yves, Case, David A., Turner, Christopher J., Stubbe, JoAnne
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248740/
https://www.ncbi.nlm.nih.gov/pubmed/18025040
http://dx.doi.org/10.1093/nar/gkm622