The ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cells

The mammalian ERCC1-XPF endonuclease has a suggested role in the repair of DNA double-strand breaks (DSB) by single-strand annealing (SSA). Here, we investigated the role of ERCC1 in homologous recombination in mammalian cells, and confirm a role of ERCC1 in SSA. Interestingly, we also report an une...

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Detalles Bibliográficos
Autores principales: Al-Minawi, Ali Z., Saleh-Gohari, Nasrollah, Helleday, Thomas
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248766/
https://www.ncbi.nlm.nih.gov/pubmed/17962301
http://dx.doi.org/10.1093/nar/gkm888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248766/
https://www.ncbi.nlm.nih.gov/pubmed/17962301
http://dx.doi.org/10.1093/nar/gkm888

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