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The ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cells
The mammalian ERCC1-XPF endonuclease has a suggested role in the repair of DNA double-strand breaks (DSB) by single-strand annealing (SSA). Here, we investigated the role of ERCC1 in homologous recombination in mammalian cells, and confirm a role of ERCC1 in SSA. Interestingly, we also report an une...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248766/ https://www.ncbi.nlm.nih.gov/pubmed/17962301 http://dx.doi.org/10.1093/nar/gkm888 |