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Mutation of the arginine finger in the active site of Escherichia coli DbpA abolishes ATPase and helicase activity and confers a dominant slow growth phenotype
Escherichia coli DEAD-box protein A (DbpA) is an ATP-dependent RNA helicase with specificity for 23S ribosomal RNA. Although DbpA has been extensively characterized biochemically, its biological function remains unknown. Previous work has shown that a DbpA deletion strain is viable with little or no...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Oxford University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248767/ https://www.ncbi.nlm.nih.gov/pubmed/17986459 http://dx.doi.org/10.1093/nar/gkm926 |