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Mammary tuberculosis mimicking breast cancer: a case report

INTRODUCTION: The incidence of tuberculosis is rising worldwide and rare manifestations of the past are seen more often nowadays. Mammary tuberculosis is a rare clinical entity, often mimicking breast cancer or abscesses of benign or malignant origin. Clinical awareness is necessary during diagnosti...

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Autores principales: Maroulis, Ioannis, Spyropoulos, Charalambos, Zolota, Vasiliki, Tzorakoleftherakis, Evaggelos
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249603/
https://www.ncbi.nlm.nih.gov/pubmed/18241336
http://dx.doi.org/10.1186/1752-1947-2-34
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author Maroulis, Ioannis
Spyropoulos, Charalambos
Zolota, Vasiliki
Tzorakoleftherakis, Evaggelos
author_facet Maroulis, Ioannis
Spyropoulos, Charalambos
Zolota, Vasiliki
Tzorakoleftherakis, Evaggelos
author_sort Maroulis, Ioannis
collection PubMed
description INTRODUCTION: The incidence of tuberculosis is rising worldwide and rare manifestations of the past are seen more often nowadays. Mammary tuberculosis is a rare clinical entity, often mimicking breast cancer or abscesses of benign or malignant origin. Clinical awareness is necessary during diagnostic work-up for establishing the correct diagnosis and treatment. CASE PRESENTATION: We present a case of breast tuberculosis diagnosed in a 73 year old woman at our institution. The patient presented with a palpable mass of the right breast with clinical, laboratory and mammographic findings indicative of breast carcinoma. The patient underwent lumpectomy and sentinel lymph node biopsy. Frozen section of the tumor and the sentinel node revealed "granulomatous inflammation", while gross examination confirmed the diagnosis of tuberculous mastitis. The patient received anti-tuberculosis therapy for six months with no side effects or any further complications. CONCLUSION: Breast tuberculosis is an obscure disease often mistaken for carcinoma or pyogenic abscess of the breast, especially if well-defined clinical features are absent. A high index of suspicion is required because the disease can usually be treated conservatively with current antituberculous modalities while surgical intervention is reserved for rare cases only.
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spelling pubmed-22496032008-02-22 Mammary tuberculosis mimicking breast cancer: a case report Maroulis, Ioannis Spyropoulos, Charalambos Zolota, Vasiliki Tzorakoleftherakis, Evaggelos J Med Case Reports Case Report INTRODUCTION: The incidence of tuberculosis is rising worldwide and rare manifestations of the past are seen more often nowadays. Mammary tuberculosis is a rare clinical entity, often mimicking breast cancer or abscesses of benign or malignant origin. Clinical awareness is necessary during diagnostic work-up for establishing the correct diagnosis and treatment. CASE PRESENTATION: We present a case of breast tuberculosis diagnosed in a 73 year old woman at our institution. The patient presented with a palpable mass of the right breast with clinical, laboratory and mammographic findings indicative of breast carcinoma. The patient underwent lumpectomy and sentinel lymph node biopsy. Frozen section of the tumor and the sentinel node revealed "granulomatous inflammation", while gross examination confirmed the diagnosis of tuberculous mastitis. The patient received anti-tuberculosis therapy for six months with no side effects or any further complications. CONCLUSION: Breast tuberculosis is an obscure disease often mistaken for carcinoma or pyogenic abscess of the breast, especially if well-defined clinical features are absent. A high index of suspicion is required because the disease can usually be treated conservatively with current antituberculous modalities while surgical intervention is reserved for rare cases only. BioMed Central 2008-02-01 /pmc/articles/PMC2249603/ /pubmed/18241336 http://dx.doi.org/10.1186/1752-1947-2-34 Text en Copyright © 2008 Maroulis et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Maroulis, Ioannis
Spyropoulos, Charalambos
Zolota, Vasiliki
Tzorakoleftherakis, Evaggelos
Mammary tuberculosis mimicking breast cancer: a case report
title Mammary tuberculosis mimicking breast cancer: a case report
title_full Mammary tuberculosis mimicking breast cancer: a case report
title_fullStr Mammary tuberculosis mimicking breast cancer: a case report
title_full_unstemmed Mammary tuberculosis mimicking breast cancer: a case report
title_short Mammary tuberculosis mimicking breast cancer: a case report
title_sort mammary tuberculosis mimicking breast cancer: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249603/
https://www.ncbi.nlm.nih.gov/pubmed/18241336
http://dx.doi.org/10.1186/1752-1947-2-34
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AT tzorakoleftherakisevaggelos mammarytuberculosismimickingbreastcanceracasereport