Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots

Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explor...

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Detalles Bibliográficos
Autores principales: Vasudeva, Neeru, Sharma, S. K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Original Articles – Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249740/
https://www.ncbi.nlm.nih.gov/pubmed/18317554
http://dx.doi.org/10.1093/ecam/nem003
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author Vasudeva, Neeru
Sharma, S. K.
author_facet Vasudeva, Neeru
Sharma, S. K.
author_sort Vasudeva, Neeru
collection PubMed
description Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explore the antifertility and estrogenic activity of ethanolic extract of the roots of Hibiscus rosa-sinensis Linn. A strong anti-implantation (inhibition 100%) and uterotropic activity was observed at the dose level of 400 mg/kg body weight. Histological studies were carried out to confirm this effect.
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spelling pubmed-22497402008-03-03 Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots Vasudeva, Neeru Sharma, S. K. Evid Based Complement Alternat Med Original Articles – Basic Science Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explore the antifertility and estrogenic activity of ethanolic extract of the roots of Hibiscus rosa-sinensis Linn. A strong anti-implantation (inhibition 100%) and uterotropic activity was observed at the dose level of 400 mg/kg body weight. Histological studies were carried out to confirm this effect. Oxford University Press 2008-03 2007-03-03 /pmc/articles/PMC2249740/ /pubmed/18317554 http://dx.doi.org/10.1093/ecam/nem003 Text en © 2007 The Author(s). http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles – Basic Science
Vasudeva, Neeru
Sharma, S. K.
Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots
title Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots
title_full Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots
title_fullStr Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots
title_full_unstemmed Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots
title_short Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots
title_sort post-coital antifertility activity of hibiscus rosa-sinensis linn. roots
topic Original Articles – Basic Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249740/
https://www.ncbi.nlm.nih.gov/pubmed/18317554
http://dx.doi.org/10.1093/ecam/nem003
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