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Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome

Wnt signaling activates the canonical pathway and induces the accumulation of non-phosphorylated beta-catenin (NPBC) in the nucleus. Although this pathway plays an important role in the maintenance of haematopoietic stem cells as well as in oncogenesis, the significance of nuclear NPBC remains uncle...

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Detalles Bibliográficos
Autores principales:	Xu, Jinglan, Suzuki, Momoko, Niwa, Yousuke, Hiraga, Junji, Nagasaka, Tetsuro, Ito, Masafumi, Nakamura, Shigeo, Tomita, Akihiro, Abe, Akihiro, Kiyoi, Hitoshi, Kinoshita, Tomohiro, Naoe, Tomoki
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Haematological Malignancy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253692/ https://www.ncbi.nlm.nih.gov/pubmed/18217891 http://dx.doi.org/10.1111/j.1365-2141.2007.06914.x

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