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Toll-like receptor 2 contributes to antibacterial defence against pneumolysin-deficient pneumococci

Toll-like receptors (TLRs) are pattern recognition receptors that recognize conserved molecular patterns expressed by pathogens. Pneumolysin, an intracellular toxin found in all Streptococcus pneumoniae clinical isolates, is an important virulence factor of the pneumococcus that is recognized by TLR...

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Detalles Bibliográficos
Autores principales: Dessing, Mark C, Florquin, Sandrine, Paton, James C, van der Poll, Tom
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253695/
https://www.ncbi.nlm.nih.gov/pubmed/17711480
http://dx.doi.org/10.1111/j.1462-5822.2007.01035.x