Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response

There is increasing evidence that longevity and stress resistance are connected, but the mechanism is unclear. We report that mitochondria are regulated in response to oxidative stress and calorie restriction through a shared mechanism involving peroxisome proliferator-activated receptor-γ co-activa...

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Detalles Bibliográficos
Autores principales: Anderson, Rozalyn M, Barger, Jamie L, Edwards, Michael G, Braun, Kristina H, O’Connor, Clare E, Prolla, Tomas A, Weindruch, Richard
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253697/
https://www.ncbi.nlm.nih.gov/pubmed/18031569
http://dx.doi.org/10.1111/j.1474-9726.2007.00357.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253697/
https://www.ncbi.nlm.nih.gov/pubmed/18031569
http://dx.doi.org/10.1111/j.1474-9726.2007.00357.x

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