Novel Triazine JPC-2067-B Inhibits Toxoplasma gondii In Vitro and In Vivo

BACKGROUND AND METHODOLOGY: Toxoplasma gondii causes substantial morbidity, mortality, and costs for healthcare in the developed and developing world. Current medicines are not well tolerated and cause hypersensitivity reactions. The dihydrotriazine JPC-2067-B (4, 6-diamino-1, 2-dihydro-2, 2-dimethy...

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Detalles Bibliográficos
Autores principales: Mui, Ernest J., Schiehser, Guy A., Milhous, Wilbur K., Hsu, Honghue, Roberts, Craig W., Kirisits, Michael, Muench, Stephen, Rice, David, Dubey, J. P., Fowble, Joseph W., Rathod, Pradipsinh K., Queener, Sherry F., Liu, Susan R., Jacobus, David P., McLeod, Rima
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254147/
https://www.ncbi.nlm.nih.gov/pubmed/18320016
http://dx.doi.org/10.1371/journal.pntd.0000190

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