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Endomyocardial Fibrosis: Still a Mystery after 60 Years
The pathologist Jack N. P. Davies identified endomyocardial fibrosis in Uganda in 1947. Since that time, reports of this restrictive cardiomyopathy have come from other parts of tropical Africa, South Asia, and South America. In Kampala, the disease accounts for 20% of heart disease patients referre...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254164/ https://www.ncbi.nlm.nih.gov/pubmed/18301727 http://dx.doi.org/10.1371/journal.pntd.0000097 |
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author | Bukhman, Gene Ziegler, John Parry, Eldryd |
author_facet | Bukhman, Gene Ziegler, John Parry, Eldryd |
author_sort | Bukhman, Gene |
collection | PubMed |
description | The pathologist Jack N. P. Davies identified endomyocardial fibrosis in Uganda in 1947. Since that time, reports of this restrictive cardiomyopathy have come from other parts of tropical Africa, South Asia, and South America. In Kampala, the disease accounts for 20% of heart disease patients referred for echocardiography. We conducted a systematic review of research on the epidemiology and etiology of endomyocardial fibrosis. We relied primarily on articles in the MEDLINE database with either “endomyocardial fibrosis” or “endomyocardial sclerosis” in the title. The volume of publications on endomyocardial fibrosis has declined since the 1980s. Despite several hypotheses regarding cause, no account of the etiology of this disease has yet fully explained its unique geographical distribution. |
format | Text |
id | pubmed-2254164 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-22541642008-02-27 Endomyocardial Fibrosis: Still a Mystery after 60 Years Bukhman, Gene Ziegler, John Parry, Eldryd PLoS Negl Trop Dis Review The pathologist Jack N. P. Davies identified endomyocardial fibrosis in Uganda in 1947. Since that time, reports of this restrictive cardiomyopathy have come from other parts of tropical Africa, South Asia, and South America. In Kampala, the disease accounts for 20% of heart disease patients referred for echocardiography. We conducted a systematic review of research on the epidemiology and etiology of endomyocardial fibrosis. We relied primarily on articles in the MEDLINE database with either “endomyocardial fibrosis” or “endomyocardial sclerosis” in the title. The volume of publications on endomyocardial fibrosis has declined since the 1980s. Despite several hypotheses regarding cause, no account of the etiology of this disease has yet fully explained its unique geographical distribution. Public Library of Science 2008-02-27 /pmc/articles/PMC2254164/ /pubmed/18301727 http://dx.doi.org/10.1371/journal.pntd.0000097 Text en Bukhman et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Review Bukhman, Gene Ziegler, John Parry, Eldryd Endomyocardial Fibrosis: Still a Mystery after 60 Years |
title | Endomyocardial Fibrosis: Still a Mystery after 60 Years |
title_full | Endomyocardial Fibrosis: Still a Mystery after 60 Years |
title_fullStr | Endomyocardial Fibrosis: Still a Mystery after 60 Years |
title_full_unstemmed | Endomyocardial Fibrosis: Still a Mystery after 60 Years |
title_short | Endomyocardial Fibrosis: Still a Mystery after 60 Years |
title_sort | endomyocardial fibrosis: still a mystery after 60 years |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254164/ https://www.ncbi.nlm.nih.gov/pubmed/18301727 http://dx.doi.org/10.1371/journal.pntd.0000097 |
work_keys_str_mv | AT bukhmangene endomyocardialfibrosisstillamysteryafter60years AT zieglerjohn endomyocardialfibrosisstillamysteryafter60years AT parryeldryd endomyocardialfibrosisstillamysteryafter60years |