MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis

BACKGROUND: MicroRNAs (miRNAs) are critical regulators of transcriptional and post-transcriptional gene silencing, which are involved in multiple developmental processes in many organisms. Apart from miRNAs, mouse germ cells express another type of small RNA, piwi-interacting RNAs (piRNAs). Although...

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Detalles Bibliográficos
Autores principales: Hayashi, Katsuhiko, Chuva de Sousa Lopes, Susana M., Kaneda, Masahiro, Tang, Fuchou, Hajkova, Petra, Lao, Kaiqin, O'Carroll, Donal, Das, Partha P., Tarakhovsky, Alexander, Miska, Eric A., Surani, M. Azim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254191/
https://www.ncbi.nlm.nih.gov/pubmed/18320056
http://dx.doi.org/10.1371/journal.pone.0001738

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