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Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells?

BACKGROUND: Smoking is the most important cause for the development of COPD. Since not all smokers develop COPD, it is obvious that other factors must be involved in disease development. We hypothesize that heme oxygenase-1 (HO-1), a protective enzyme against oxidative stress and inflammation, is in...

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Detalles Bibliográficos
Autores principales: Brandsma, Corry-Anke, Hylkema, Machteld N, van der Strate, Barry WA, Slebos, Dirk-Jan, Luinge, Marjan A, Geerlings, Marie, Timens, Wim, Postma, Dirkje S, Kerstjens, Huib AM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254411/
https://www.ncbi.nlm.nih.gov/pubmed/18252008
http://dx.doi.org/10.1186/1465-9921-9-17