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Importance of TP53 codon 72 and intron 3 duplication 16bp polymorphisms in prediction of susceptibility on breast cancer

BACKGROUND: TP53 is one of major tumour suppressor genes being essential in preservation of genome integrity. Two very common polymorphisms have been demonstrated to contribute to cancer susceptibility and tumour behaviour. The purpose of this study was to evaluate the role of Arg72Pro and PIN3 Ins1...

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Detalles Bibliográficos
Autores principales:	Costa, Sandra, Pinto, Daniela, Pereira, Deolinda, Rodrigues, Helena, Cameselle-Teijeiro, Jorge, Medeiros, Rui, Schmitt, Fernando
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254432/ https://www.ncbi.nlm.nih.gov/pubmed/18230179 http://dx.doi.org/10.1186/1471-2407-8-32

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