Cargando…

Intravenous administration of the conditionally replicative adenovirus Ad5-Δ24RGD induces regression of osteosarcoma lung metastases

Metastatic osteosarcoma (OS) has a very poor prognosis. New treatments are therefore wanted. The conditionally replicative adenovirus Ad5-Δ24RGD has shown promising anti-tumor effects on local cancers, including OS. The purpose of this study was to determine whether intravenous administration of Ad5...

Descripción completa

Detalles Bibliográficos
Autores principales:	Graat, Harm CA, van Beusechem, Victor W, Schagen, Frederik HE, Witlox, M Adhiambo, Kleinerman, Eugenie S, Helder, Marco N, Gerritsen, Winald R, Kaspers, Gertjan JL, Wuisman, Paul IJM
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254437/ https://www.ncbi.nlm.nih.gov/pubmed/18215325 http://dx.doi.org/10.1186/1476-4598-7-9

Ejemplares similares

Different susceptibility of osteosarcoma cell lines and primary cells to treatment with oncolytic adenovirus and doxorubicin or cisplatin
por: Graat, H C A, et al.
Publicado: (2006)

WEE1 inhibition sensitizes osteosarcoma to radiotherapy
por: PosthumaDeBoer, Jantine, et al.
Publicado: (2011)

Convection Enhanced Delivery of the Oncolytic Adenovirus Delta24-RGD in Patients with Recurrent GBM: A Phase I Clinical Trial Including Correlative Studies
por: van Putten, Erik H.P., et al.
Publicado: (2022)

Osteosarcoma Overview
por: Lindsey, Brock A., et al.
Publicado: (2016)

Epigenetic Regulation of Apoptosis and Cell Cycle in Osteosarcoma
por: Rao-Bindal, Krithi, et al.
Publicado: (2011)

Combination of NK cells therapy and oral administration of entinostat as an approach for osteosarcoma lung metastasis treatment
por: Kiany, Simin, et al.
Publicado: (2015)

Pramlintide: A Novel Therapeutic Approach for Osteosarcoma through Metabolic Reprogramming
por: Yang, Yuanzheng, et al.
Publicado: (2022)

Promoting NK cell trafficking to improve therapeutic effect of NK cell therapy on osteosarcoma
por: Yang, Yuanzheng, et al.
Publicado: (2015)

Small cell osteosarcoma of a toe phalanx: a case report and review of literature
por: PosthumaDeBoer, Jantine, et al.
Publicado: (2010)

Exosomal communication by metastatic osteosarcoma cells modulates alveolar macrophages to an M2 tumor-promoting phenotype and inhibits tumoricidal functions
por: Wolf-Dennen, Kerri, et al.
Publicado: (2020)

Molecular alterations as target for therapy in metastatic osteosarcoma: a review of literature
por: PosthumaDeBoer, J., et al.
Publicado: (2011)

Targeting JNK-interacting protein 1 (JIP1) sensitises osteosarcoma to doxorubicin
por: De Boer, Jantine Posthuma, et al.
Publicado: (2012)

Immune modulation through targeting PD-1/PDL-1 signaling pathway for the treatment of osteosarcoma lung metastastasis
por: Dhupkar, Pooja M, et al.
Publicado: (2015)

Enhanced Transduction and Replication of RGD-Fiber Modified Adenovirus in Primary T Cells
por: Sengupta, Sadhak, et al.
Publicado: (2011)

Short-fibre modification facilitates adenovirus-mediated gene delivery in rheumatoid arthritis synoviocytes and synovium: role of RGD and non-RGD binding integrins
por: Toh, M-L, et al.
Publicado: (2005)

Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells
por: Hollomon, Mario G, et al.
Publicado: (2013)

Glucosamine and chondroitin sulfate supplementation to treat symptomatic disc degeneration: Biochemical rationale and case report
por: van Blitterswijk, Wim J, et al.
Publicado: (2003)

Knock down of Fas-Associated Protein with Death Domain (FADD) Sensitizes Osteosarcoma to TNFα-induced Cell Death
por: Hollomon, Mario G., et al.
Publicado: (2020)

The In Vivo Therapeutic Efficacy of the Oncolytic Adenovirus Delta24-RGD Is Mediated by Tumor-Specific Immunity
por: Kleijn, Anne, et al.
Publicado: (2014)

Delta-24-RGD Oncolytic Adenovirus Elicits Anti-Glioma Immunity in an Immunocompetent Mouse Model
por: Jiang, Hong, et al.
Publicado: (2014)

Potentiation of radiation therapy by the oncolytic adenovirus dl1520 (ONYX-015) in human malignant glioma xenografts
por: Geoerger, B, et al.
Publicado: (2003)

Aerosol Gemcitabine after Amputation Inhibits Osteosarcoma Lung Metastases but Not Wound Healing
por: Kleinerman, Eugenie S., et al.
Publicado: (2018)

Surface proteomic analysis of osteosarcoma identifies EPHA2 as receptor for targeted drug delivery
por: PosthumaDeBoer, J, et al.
Publicado: (2013)

Unleashing the Full Potential of Oncolytic Adenoviruses against Cancer by Applying RNA Interference: The Force Awakens
por: Brachtlova, Tereza, et al.
Publicado: (2018)

Using the Spleen as an In Vivo Systemic Immune Barometer Alongside Osteosarcoma Disease Progression and Immunotherapy with α-PD-L1
por: Markel, Justin E., et al.
Publicado: (2018)

The Adenovirus Type 3 Dodecahedron's RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding
por: Gout, E., et al.
Publicado: (2010)

Spatial and temporal proteome dynamics of glioma cells during oncolytic adenovirus Delta-24-RGD infection
por: González-Morales, Andrea, et al.
Publicado: (2018)

In vitro gentamicin release from commercially available calcium-phosphate bone substitutes influence of carrier type on duration of the release profile
por: Stallmann, Hein P, et al.
Publicado: (2006)

RGD-modifided oncolytic adenovirus exhibited potent cytotoxic effect on CAR-negative bladder cancer-initiating cells
por: Yang, Y, et al.
Publicado: (2015)

Evidence of Anti-tumoral Efficacy in an Immune Competent Setting with an iRGD-Modified Hyaluronidase-Armed Oncolytic Adenovirus
por: Al-Zaher, Ahmed Abdullah, et al.
Publicado: (2018)

GITRL-armed Delta-24-RGD oncolytic adenovirus prolongs survival and induces anti-glioma immune memory
por: Rivera-Molina, Yisel, et al.
Publicado: (2019)

Current and Emerging Treatment Options for Castration-Resistant Prostate Cancer: A Focus on Immunotherapy
por: Gerritsen, Winald R., et al.
Publicado: (2011)

Tumor Vessel Development and Expansion in Ewing's Sarcoma: A Review of the Vasculogenesis Process and Clinical Trials with Vascular-Targeting Agents
por: Stewart, Keri S., et al.
Publicado: (2011)

Locally-Delivered T-Cell-Derived Cellular Vehicles Efficiently Track and Deliver Adenovirus Delta24-RGD to Infiltrating Glioma
por: Balvers, Rutger K., et al.
Publicado: (2014)

Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy
por: Santiago-O’Farrill, Janice M., et al.
Publicado: (2017)

A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultracentrifugation
por: Stepanenko, Aleksei A., et al.
Publicado: (2021)

Exercise intervention decreases acute and late doxorubicin‐induced cardiotoxicity
por: Wang, Fei, et al.
Publicado: (2021)

The Innate Immune System in Cardiovascular Diseases and Its Role in Doxorubicin-Induced Cardiotoxicity
por: Bhagat, Anchit, et al.
Publicado: (2022)

An efficient method for the transduction of primary pediatric glioma neurospheres
por: Meel, Michaël H., et al.
Publicado: (2018)

Acute myeloid leukaemia niche regulates response to L‐asparaginase
por: Kaspers, Gertjan J. L.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_36le4avhuaad0ec62mg4h3bd08