Estimating effects of rare haplotypes on failure time using a penalized Cox proportional hazards regression model

BACKGROUND: This paper describes a likelihood approach to model the relation between failure time and haplotypes in studies with unrelated individuals where haplotype phase is unknown, while dealing with the problem of unstable estimates due to rare haplotypes by considering a penalized log-likeliho...

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Detalles Bibliográficos
Autores principales: Souverein, Olga W, Zwinderman, Aeilko H, Jukema, J Wouter, Tanck, Michael WT
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254440/
https://www.ncbi.nlm.nih.gov/pubmed/18221501
http://dx.doi.org/10.1186/1471-2156-9-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254440/
https://www.ncbi.nlm.nih.gov/pubmed/18221501
http://dx.doi.org/10.1186/1471-2156-9-9

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