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UV-A-induced structural and functional changes in human lens deamidated αB-crystallin

PURPOSE: To determine comparative effects of ultraviolet (UV)-A irradiation on structural and functional properties of wild type (WT) αB-crystallin and its three deamidated mutant proteins (αB-Asn78Asp, αB-Asn146Asp, and αB-Asn78/146Asp). METHODS: Three deamidated mutants previously generated from r...

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Detalles Bibliográficos
Autores principales: Mafia, Kerri, Gupta, Ratna, Kirk, Marion, Wilson, L., Srivastava, O.P., Barnes, Stephen
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2255029/
https://www.ncbi.nlm.nih.gov/pubmed/18334940