Cargando…
UV-A-induced structural and functional changes in human lens deamidated αB-crystallin
PURPOSE: To determine comparative effects of ultraviolet (UV)-A irradiation on structural and functional properties of wild type (WT) αB-crystallin and its three deamidated mutant proteins (αB-Asn78Asp, αB-Asn146Asp, and αB-Asn78/146Asp). METHODS: Three deamidated mutants previously generated from r...
Autores principales: | Mafia, Kerri, Gupta, Ratna, Kirk, Marion, Wilson, L., Srivastava, O.P., Barnes, Stephen |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2255029/ https://www.ncbi.nlm.nih.gov/pubmed/18334940 |
Ejemplares similares
-
Structural and functional roles of deamidation of N146 and/or truncation of NH(2)- or COOH-termini in human αB-crystallin
por: Asomugha, C.O., et al.
Publicado: (2011) -
Interaction of βA3-Crystallin with Deamidated Mutants of αA- and αB-Crystallins
por: Tiwary, Ekta, et al.
Publicado: (2015) -
Deamidation alters interactions of β-crystallins in hetero-oligomers
por: Takata, Takumi, et al.
Publicado: (2009) -
A serine-type protease activity of human lens βA3-crystallin is responsible for its autodegradation
por: Gupta, R., et al.
Publicado: (2010) -
Post-translationally modified human lens crystallin fragments show aggregation in vitro
por: Srivastava, O.P., et al.
Publicado: (2017)