Virulence factor rtx in Legionella pneumophila, evidence suggesting it is a modular multifunctional protein

BACKGROUND: The repeats in toxin (Rtx) are an important pathogenicity factor involved in host cells invasion of Legionella pneumophila and other pathogenic bacteria. Its role in escaping the host immune system and cytotoxic activity is well known. Its repeated motives and modularity make Rtx a multi...

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Detalles Bibliográficos
Autores principales: D'Auria, Giuseppe, Jiménez, Núria, Peris-Bondia, Francesc, Pelaz, Carmen, Latorre, Amparo, Moya, Andrés
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2257941/
https://www.ncbi.nlm.nih.gov/pubmed/18194518
http://dx.doi.org/10.1186/1471-2164-9-14