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Using protein complexes to predict phenotypic effects of gene mutation

BACKGROUND: Predicting the phenotypic effects of mutations is a central goal of genetics research; it has important applications in elucidating how genotype determines phenotype and in identifying human disease genes. RESULTS: Using a wide range of functional genomic data from the yeast Saccharomyce...

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Detalles Bibliográficos
Autores principales:	Fraser, Hunter B, Plotkin, Joshua B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258176/ https://www.ncbi.nlm.nih.gov/pubmed/18042286 http://dx.doi.org/10.1186/gb-2007-8-11-r252

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