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Integrative analysis for finding genes and networks involved in diabetes and other complex diseases

We have developed an integrative analysis method combining genetic interactions, identified using type 1 diabetes genome scan data, and a high-confidence human protein interaction network. Resulting networks were ranked by the significance of the enrichment of proteins from interacting regions. We i...

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Detalles Bibliográficos
Autores principales: Bergholdt, Regine, Størling, Zenia M, Lage, Kasper, Karlberg, E Olof, Ólason, Páll Í, Aalund, Mogens, Nerup, Jørn, Brunak, Søren, Workman, Christopher T, Pociot, Flemming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258178/
https://www.ncbi.nlm.nih.gov/pubmed/18045462
http://dx.doi.org/10.1186/gb-2007-8-11-r253