Cargando…

Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia

BACKGROUND: Previously reported evidence indicates that pigs were independently domesticated in multiple places throughout the world. However, a detailed picture of the origin and dispersal of domestic pigs in East Asia has not yet been reported. RESULTS: Population phylogenomic analysis was conduct...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Gui-Sheng, Yao, Yong-Gang, Qu, Kai-Xing, Ding, Zhao-Li, Li, Hui, Palanichamy, Malliya G, Duan, Zi-Yuan, Li, Ning, Chen, Yao-Sheng, Zhang, Ya-Ping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258183/
https://www.ncbi.nlm.nih.gov/pubmed/18021448
http://dx.doi.org/10.1186/gb-2007-8-11-r245
_version_ 1782151324279767040
author Wu, Gui-Sheng
Yao, Yong-Gang
Qu, Kai-Xing
Ding, Zhao-Li
Li, Hui
Palanichamy, Malliya G
Duan, Zi-Yuan
Li, Ning
Chen, Yao-Sheng
Zhang, Ya-Ping
author_facet Wu, Gui-Sheng
Yao, Yong-Gang
Qu, Kai-Xing
Ding, Zhao-Li
Li, Hui
Palanichamy, Malliya G
Duan, Zi-Yuan
Li, Ning
Chen, Yao-Sheng
Zhang, Ya-Ping
author_sort Wu, Gui-Sheng
collection PubMed
description BACKGROUND: Previously reported evidence indicates that pigs were independently domesticated in multiple places throughout the world. However, a detailed picture of the origin and dispersal of domestic pigs in East Asia has not yet been reported. RESULTS: Population phylogenomic analysis was conducted in domestic pigs and wild boars by screening the haplogroup-specific mutation motifs inferred from a phylogenetic tree of pig complete mitochondrial DNA (mtDNA) sequences. All domestic pigs are clustered into single clade D (which contains subclades D1, D2, D3, and D4), with wild boars from East Asia being interspersed. Three haplogroups within D1 are dominant in the Mekong region (D1a2 and D1b) and the middle and downstream regions of the Yangtze River (D1a1a), and may represent independent founders of domestic pigs. None of the domestic pig samples from North East Asia, the Yellow River region, and the upstream region of the Yangtze River share the same haplogroup status with the local wild boars. The limited regional distributions of haplogroups D1 (including its subhaplogroups), D2, D3, and D4 in domestic pigs suggest at least two different in situ domestication events. CONCLUSION: The use of fine-grained mtDNA phylogenomic analysis of wild boars and domestic pigs is a powerful tool with which to discern the origin of domestic pigs. Our findings show that pig domestication in East Asia mainly occurred in the Mekong region and the middle and downstream regions of the Yangtze River.
format Text
id pubmed-2258183
institution National Center for Biotechnology Information
language English
publishDate 2007
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-22581832008-02-28 Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia Wu, Gui-Sheng Yao, Yong-Gang Qu, Kai-Xing Ding, Zhao-Li Li, Hui Palanichamy, Malliya G Duan, Zi-Yuan Li, Ning Chen, Yao-Sheng Zhang, Ya-Ping Genome Biol Research BACKGROUND: Previously reported evidence indicates that pigs were independently domesticated in multiple places throughout the world. However, a detailed picture of the origin and dispersal of domestic pigs in East Asia has not yet been reported. RESULTS: Population phylogenomic analysis was conducted in domestic pigs and wild boars by screening the haplogroup-specific mutation motifs inferred from a phylogenetic tree of pig complete mitochondrial DNA (mtDNA) sequences. All domestic pigs are clustered into single clade D (which contains subclades D1, D2, D3, and D4), with wild boars from East Asia being interspersed. Three haplogroups within D1 are dominant in the Mekong region (D1a2 and D1b) and the middle and downstream regions of the Yangtze River (D1a1a), and may represent independent founders of domestic pigs. None of the domestic pig samples from North East Asia, the Yellow River region, and the upstream region of the Yangtze River share the same haplogroup status with the local wild boars. The limited regional distributions of haplogroups D1 (including its subhaplogroups), D2, D3, and D4 in domestic pigs suggest at least two different in situ domestication events. CONCLUSION: The use of fine-grained mtDNA phylogenomic analysis of wild boars and domestic pigs is a powerful tool with which to discern the origin of domestic pigs. Our findings show that pig domestication in East Asia mainly occurred in the Mekong region and the middle and downstream regions of the Yangtze River. BioMed Central 2007 2007-11-19 /pmc/articles/PMC2258183/ /pubmed/18021448 http://dx.doi.org/10.1186/gb-2007-8-11-r245 Text en Copyright © 2007 Wu et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Wu, Gui-Sheng
Yao, Yong-Gang
Qu, Kai-Xing
Ding, Zhao-Li
Li, Hui
Palanichamy, Malliya G
Duan, Zi-Yuan
Li, Ning
Chen, Yao-Sheng
Zhang, Ya-Ping
Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia
title Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia
title_full Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia
title_fullStr Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia
title_full_unstemmed Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia
title_short Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia
title_sort population phylogenomic analysis of mitochondrial dna in wild boars and domestic pigs revealed multiple domestication events in east asia
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258183/
https://www.ncbi.nlm.nih.gov/pubmed/18021448
http://dx.doi.org/10.1186/gb-2007-8-11-r245
work_keys_str_mv AT wuguisheng populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT yaoyonggang populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT qukaixing populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT dingzhaoli populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT lihui populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT palanichamymalliyag populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT duanziyuan populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT lining populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT chenyaosheng populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia
AT zhangyaping populationphylogenomicanalysisofmitochondrialdnainwildboarsanddomesticpigsrevealedmultipledomesticationeventsineastasia