Application of phage display to high throughput antibody generation and characterization

We have created a high quality phage display library containing over 10(10 )human antibodies and describe its use in the generation of antibodies on an unprecedented scale. We have selected, screened and sequenced over 38,000 recombinant antibodies to 292 antigens, yielding over 7,200 unique clones....

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Detalles Bibliográficos
Autores principales: Schofield, Darren J, Pope, Anthony R, Clementel, Veronica, Buckell, Jenny, Chapple, Susan DJ, Clarke, Kay F, Conquer, Jennie S, Crofts, Anna M, Crowther, Sandra RE, Dyson, Michael R, Flack, Gillian, Griffin, Gareth J, Hooks, Yvette, Howat, William J, Kolb-Kokocinski, Anja, Kunze, Susan, Martin, Cecile D, Maslen, Gareth L, Mitchell, Joanne N, O'Sullivan, Maureen, Perera, Rajika L, Roake, Wendy, Shadbolt, S Paul, Vincent, Karen J, Warford, Anthony, Wilson, Wendy E, Xie, Jane, Young, Joyce L, McCafferty, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258204/
https://www.ncbi.nlm.nih.gov/pubmed/18047641
http://dx.doi.org/10.1186/gb-2007-8-11-r254

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