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Positive Feedback and Noise Activate the Stringent Response Regulator Rel in Mycobacteria

Phenotypic heterogeneity in an isogenic, microbial population enables a subset of the population to persist under stress. In mycobacteria, stresses like nutrient and oxygen deprivation activate the stress response pathway involving the two-component system MprAB and the sigma factor, SigE. SigE in t...

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Detalles Bibliográficos
Autores principales:	Sureka, Kamakshi, Ghosh, Bhaswar, Dasgupta, Arunava, Basu, Joyoti, Kundu, Manikuntala, Bose, Indrani
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258413/ https://www.ncbi.nlm.nih.gov/pubmed/18335046 http://dx.doi.org/10.1371/journal.pone.0001771

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