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Regulation of apoptosis-inducing factor-mediated, cisplatin-induced apoptosis by Akt
Cisplatin is a first-line chemotherapeutic for ovarian cancer, although chemoresistance limits treatment success. Apoptosis, an important determinant of cisplatin sensitivity, occurs via caspase-dependent and -independent mechanisms. Activation of the protein kinase Akt, commonly observed in ovarian...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259169/ https://www.ncbi.nlm.nih.gov/pubmed/18283299 http://dx.doi.org/10.1038/sj.bjc.6604223 |