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Simulating non-small cell lung cancer with a multiscale agent-based model

BACKGROUND: The epidermal growth factor receptor (EGFR) is frequently overexpressed in many cancers, including non-small cell lung cancer (NSCLC). In silico modeling is considered to be an increasingly promising tool to add useful insights into the dynamics of the EGFR signal transduction pathway. H...

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Detalles Bibliográficos
Autores principales: Wang, Zhihui, Zhang, Le, Sagotsky, Jonathan, Deisboeck, Thomas S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259313/
https://www.ncbi.nlm.nih.gov/pubmed/18154660
http://dx.doi.org/10.1186/1742-4682-4-50