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Mutation analysis of the MDM4 gene in German breast cancer patients

BACKGROUND: MDM4 is a negative regulator of p53 and cooperates with MDM2 in the cellular response to DNA damage. It is unknown, however, whether MDM4 gene alterations play some role in the inherited component of breast cancer susceptibility. METHODS: We sequenced the whole MDM4 coding region and fla...

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Detalles Bibliográficos
Autores principales:	Reincke, Scarlett, Govbakh, Lina, Wilhelm, Bettina, Jin, Haiyan, Bogdanova, Natalia, Bremer, Michael, Karstens, Johann H, Dörk, Thilo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259322/ https://www.ncbi.nlm.nih.gov/pubmed/18279506 http://dx.doi.org/10.1186/1471-2407-8-52

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