A novel mutant of the Sup35 protein of Saccharomyces cerevisiae defective in translation termination and in GTPase activity still supports cell viability

BACKGROUND: When a stop codon is located in the ribosomal A-site, the termination complex promotes release of the polypeptide and dissociation of the 80S ribosome. In eukaryotes two proteins eRF1 and eRF3 play a crucial function in the termination process. The essential GTPase Sup35p, the eRF3 relea...

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Detalles Bibliográficos
Autores principales: Fabret, Céline, Cosnier, Bruno, Lekomtsev, Sergey, Gillet, Sylvie, Hatin, Isabelle, Le Maréchal, Pierre, Rousset, Jean Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259375/
https://www.ncbi.nlm.nih.gov/pubmed/18267004
http://dx.doi.org/10.1186/1471-2199-9-22

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