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Modelling the structures of G protein-coupled receptors aided by three-dimensional validation
BACKGROUND: G protein-coupled receptors (GPCRs) are abundant, activate complex signalling and represent the targets for up to ~60% of pharmaceuticals but there is a paucity of structural data. Bovine rhodopsin is the first GPCR for which high-resolution structures have been completed but significant...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259415/ https://www.ncbi.nlm.nih.gov/pubmed/18315845 http://dx.doi.org/10.1186/1471-2105-9-S1-S14 |