A novel method to quantify local CpG methylation density by regional methylation elongation assay on microarray

BACKGROUND: DNA methylation based techniques are important tools in both clinical diagnostics and therapeutics. But most of these methods only analyze a few CpG sites in a target region. Indeed, difference of site-specific methylation may also lead to a change of methylation density in many cases, a...

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Detalles Bibliográficos
Autores principales: Zhang, Dingdong, Wang, Yan, Bai, Yunfei, Ge, Qinyu, Qiao, Yingjuan, Luo, Junfeng, Jia, Chao, Lu, Zuhong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262069/
https://www.ncbi.nlm.nih.gov/pubmed/18237388
http://dx.doi.org/10.1186/1471-2164-9-59

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