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The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion
BACKGROUND: The HIV-1 envelope glycoprotein gp120, which mediates viral attachment to target cells, consists for ~50% of sugar, but the role of the individual sugar chains in various aspects of gp120 folding and function is poorly understood. Here we studied the role of the carbohydrate at position...
Autores principales: | Sanders, Rogier W, van Anken, Eelco, Nabatov, Alexei A, Liscaljet, I Marije, Bontjer, Ilja, Eggink, Dirk, Melchers, Mark, Busser, Els, Dankers, Martijn M, Groot, Fedde, Braakman, Ineke, Berkhout, Ben, Paxton, William A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262092/ https://www.ncbi.nlm.nih.gov/pubmed/18237398 http://dx.doi.org/10.1186/1742-4690-5-10 |
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