Conservation Patterns of HIV-1 RT Connection and RNase H Domains: Identification of New Mutations in NRTI-Treated Patients

BACKGROUND: Although extensive HIV drug resistance information is available for the first 400 amino acids of its reverse transcriptase, the impact of antiretroviral treatment in C-terminal domains of Pol (thumb, connection and RNase H) is poorly understood. METHODS AND FINDINGS: We wanted to charact...

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Detalles Bibliográficos
Autores principales: Santos, André F. A., Lengruber, Renan B., Soares, Esmeralda A., Jere, Abhay, Sprinz, Eduardo, Martinez, Ana M. B., Silveira, Jussara, Sion, Fernando S., Pathak, Vinay K., Soares, Marcelo A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262134/
https://www.ncbi.nlm.nih.gov/pubmed/18335052
http://dx.doi.org/10.1371/journal.pone.0001781

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