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Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LβT2 gonadotrophs

We have shown previously that, in sheep primary pituitary cells, bone morphogenetic proteins (BMP)-4 inhibits FSHβ mRNA expression and FSH release. In contrast, in mouse LβT2 gonadotrophs, others have shown a stimulatory effect of BMPs on basal or activin-stimulated FSHβ promoter-driven transcriptio...

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Detalles Bibliográficos
Autores principales:	Nicol, L, Faure, M-O, McNeilly, J R, Fontaine, J, Taragnat, C, McNeilly, A S
Formato:	Texto
Lenguaje:	English
Publicado:	BioScientifica 2008
Materias:	Regular papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262182/ https://www.ncbi.nlm.nih.gov/pubmed/18310445 http://dx.doi.org/10.1677/JOE-07-0542

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