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Analysis of the transcriptional activity of endogenous NFAT5 in primary cells using transgenic NFAT-luciferase reporter mice
BACKGROUND: The transcription factor NFAT5/TonEBP regulates the response of mammalian cells to hypertonicity. However, little is known about the physiopathologic tonicity thresholds that trigger its transcriptional activity in primary cells. Wilkins et al. recently developed a transgenic mouse carry...
Autores principales: | Morancho, Beatriz, Minguillón, Jordi, Molkentin, Jeffery D, López-Rodríguez, Cristina, Aramburu, Jose |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262899/ https://www.ncbi.nlm.nih.gov/pubmed/18221508 http://dx.doi.org/10.1186/1471-2199-9-13 |
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