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Self-regulated mechanism of Plk1 localization to kinetochores: lessons from the Plk1-PBIP1 interaction

Mammalian polo-like kinase 1 (Plk1) has been studied extensively as a critical element in regulating various mitotic events during M-phase progression. Plk1 function is spatially regulated through the targeting activity of the conserved polo-box domain (PBD) present in the C-terminal non-catalytic r...

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Detalles Bibliográficos
Autores principales: Lee, Kyung S, Oh, Doo-Yi, Kang, Young H, Park, Jung-Eun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263035/
https://www.ncbi.nlm.nih.gov/pubmed/18215321
http://dx.doi.org/10.1186/1747-1028-3-4