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Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans
The initiation of transcription and replication of influenza A virus requires the 5' and 3' ends of vRNA. Here, the role of segment-specific non-coding sequences of influenza A virus on viral RNA synthesis was studied. Recombinant viruses, with the nonstructural protein (NS) segment-specif...
Autores principales: | Ng, Stella SF, Li, Olive TW, Cheung, Timothy KW, Malik Peiris, J S, Poon, Leo LM |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263042/ https://www.ncbi.nlm.nih.gov/pubmed/18186945 http://dx.doi.org/10.1186/1743-422X-5-2 |
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