Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?

The precise role of the O-fucosyltransferase Ofut1 in Notch-receptor trafficking has remained controversial. A recent study sheds new light on the non-catalytic activity of Ofut1 and provides further evidence that Ofut1 acts as a chaperone in the endoplasmic reticulum.

Detalles Bibliográficos
Autores principales: Vodovar, Nicolas, Schweisguth, François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263122/
https://www.ncbi.nlm.nih.gov/pubmed/18312702
http://dx.doi.org/10.1186/jbiol68
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author Vodovar, Nicolas
Schweisguth, François
author_facet Vodovar, Nicolas
Schweisguth, François
author_sort Vodovar, Nicolas
collection PubMed
description The precise role of the O-fucosyltransferase Ofut1 in Notch-receptor trafficking has remained controversial. A recent study sheds new light on the non-catalytic activity of Ofut1 and provides further evidence that Ofut1 acts as a chaperone in the endoplasmic reticulum.
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spelling pubmed-22631222008-03-07 Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy? Vodovar, Nicolas Schweisguth, François J Biol Minireview The precise role of the O-fucosyltransferase Ofut1 in Notch-receptor trafficking has remained controversial. A recent study sheds new light on the non-catalytic activity of Ofut1 and provides further evidence that Ofut1 acts as a chaperone in the endoplasmic reticulum. BioMed Central 2008 2008-02-28 /pmc/articles/PMC2263122/ /pubmed/18312702 http://dx.doi.org/10.1186/jbiol68 Text en Copyright © 2008 BioMed Central Ltd
spellingShingle Minireview
Vodovar, Nicolas
Schweisguth, François
Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?
title Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?
title_full Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?
title_fullStr Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?
title_full_unstemmed Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?
title_short Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?
title_sort functions of o-fucosyltransferase in notch trafficking and signaling: towards the end of a controversy?
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263122/
https://www.ncbi.nlm.nih.gov/pubmed/18312702
http://dx.doi.org/10.1186/jbiol68
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