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Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?

The precise role of the O-fucosyltransferase Ofut1 in Notch-receptor trafficking has remained controversial. A recent study sheds new light on the non-catalytic activity of Ofut1 and provides further evidence that Ofut1 acts as a chaperone in the endoplasmic reticulum.

Detalles Bibliográficos
Autores principales: Vodovar, Nicolas, Schweisguth, François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263122/
https://www.ncbi.nlm.nih.gov/pubmed/18312702
http://dx.doi.org/10.1186/jbiol68

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