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Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?
The precise role of the O-fucosyltransferase Ofut1 in Notch-receptor trafficking has remained controversial. A recent study sheds new light on the non-catalytic activity of Ofut1 and provides further evidence that Ofut1 acts as a chaperone in the endoplasmic reticulum.
Autores principales: | Vodovar, Nicolas, Schweisguth, François |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263122/ https://www.ncbi.nlm.nih.gov/pubmed/18312702 http://dx.doi.org/10.1186/jbiol68 |
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