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Neonatal Exposure to Low Doses of Diazinon: Long-Term Effects on Neural Cell Development and Acetylcholine Systems

BACKGROUND: The developmental neurotoxicity of organophosphate pesticides involves mechanisms other than their shared property of cholinesterase inhibition. OBJECTIVES: We gave diazinon (DZN) to newborn rats on postnatal days 1–4, using doses (0.5 or 2 mg/kg) spanning the threshold for barely detect...

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Detalles Bibliográficos
Autores principales: Slotkin, Theodore A., Bodwell, Bethany E., Levin, Edward D., Seidler, Frederic J.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265026/
https://www.ncbi.nlm.nih.gov/pubmed/18335101
http://dx.doi.org/10.1289/ehp.11005