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Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans

BACKGROUND: The spindle checkpoint delays the onset of anaphase until all sister chromatids are aligned properly at the metaphase plate. To investigate the role san-1, the MAD3 homologue, has in Caenorhabditis elegans embryos we used RNA interference (RNAi) to identify genes synthetic lethal with th...

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Detalles Bibliográficos
Autores principales: Hajeri, Vinita A, Stewart, Anil M, Moore, Landon L, Padilla, Pamela A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265278/
https://www.ncbi.nlm.nih.gov/pubmed/18248670
http://dx.doi.org/10.1186/1747-1028-3-6