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Inhibition of “self” engulfment through deactivation of myosin-II at the phagocytic synapse between human cells
Phagocytosis of foreign cells or particles by macrophages is a rapid process that is inefficient when faced with “self” cells that display CD47—although signaling mechanisms in self-recognition have remained largely unknown. With human macrophages, we show the phagocytic synapse at cell contacts inv...
Autores principales: | Tsai, Richard K., Discher, Dennis E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265407/ https://www.ncbi.nlm.nih.gov/pubmed/18332220 http://dx.doi.org/10.1083/jcb.200708043 |
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