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IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

Interferons (IFN) exert antiviral, immunomodulatory and cytostatic activities. IFN-α/β (type I IFN) and IFN-λ (type III IFN) bind distinct receptors, but regulate similar sets of genes and exhibit strikingly similar biological activities. We analyzed to what extent the IFN-α/β and IFN-λ systems over...

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Detalles Bibliográficos
Autores principales:	Sommereyns, Caroline, Paul, Sophie, Staeheli, Peter, Michiels, Thomas
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265414/ https://www.ncbi.nlm.nih.gov/pubmed/18369468 http://dx.doi.org/10.1371/journal.ppat.1000017

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